Hepatoprotective activity of Melia azedarach leaf extract against simvastatin induced Hepatotoxicity in rats

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Hepatoprotective activity of Melia azedarach leaf extract against simvastatin induced Hepatotoxicity in rats

The aim of the study is to investigate the hepatoprotective activity of Melia azedarach L leaves extracts against simvastatin induced hepatotoxicity. The phytochemical screening was carried on the leaves extracts of Melia azedarach revealed the presence of some active ingredients such as Alkaloids, Tannins, Sponginess, Phenols, glycosides, steroids, terpenoids and flavonoids. Leaves of Melia az...

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Antioxidative Activity of Melia Azedarach Linn Leaf Extract

The antioxidant activity of the melia azedarach was investigated in rats with ethanol-induced erythrocyte damage. Chronic administration of ethanol (20% w/v, 2 g/kg.p.o.,daily for four weeks) increased the level of lipid peroxidation (LPO), decreased the activity of superoxide dismutase (SOD) and catalase and reduced the content of glutathione (GSH). The concurrent treatment of ethanol-admini...

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Hepatoprotective Activity of Methanolic Extract of Melia Azedarach. L on Wistar Rats

The objective of the present study appraised the hepatoprotective activity of methanolic extract of Melia azedarach. L leaves on Wistar rats. The Methanolic extracts of Melia azedarach. L (200mg & 500mg/kg,b.w,p.o) was administered respectively to the animals which were treated with carbon tetrachloride. Its effects on biochemical parameters were compared with standard drug silymarin (100mg/kg,...

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Anti-Urolithiatic Activity of Melia Azedarach Linn Leaf Extract in Ethylene Glycol-Induced Urolithiasis in Male Albino Rats

Purpose: To investigate the anti-urolithiatic activity of the aqueous and alcoholic extracts of Melia azedarach Linn leaves in calcium oxalate urolithiasis in male albino rats. Methods: The effect of oral administration of aqueous and ethanol extracts of Melia azedarach Linn leaves on calcium oxalate urolithiasis has been investigated. Lithiasis was induced by oral adminstration of ethylene gly...

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ژورنال

عنوان ژورنال: Journal of Applied Pharmaceutical Science

سال: 2012

ISSN: 2231-3354

DOI: 10.7324/japs.2012.2721